Impaired neurogenesis, learning and memory and low seizure threshold associated with loss of neural precursor cell survivin

BACKGROUND: Survivin is a unique member of the inhibitor of apoptosis protein (IAP) family in that it exhibits antiapoptotic properties and also promotes the cell cycle and mediates mitosis as a chromosome passenger protein. Survivin is highly expressed in neural precursor cells in the brain, yet it...

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Autors principals: Coremans, Vanessa, Ahmed, Tariq, Balschun, Detlef, D'Hooge, Rudi, DeVriese, Astrid, Cremer, Jonathan, Antonucci, Flavia, Moons, Michaël, Baekelandt, Veerle, Reumers, Veerle, Cremer, Harold, Eisch, Amelia, Lagace, Diane, Janssens, Tom, Bozzi, Yuri, Caleo, Matteo, Conway, Edward M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817683/
https://ncbi.nlm.nih.gov/pubmed/20051123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-2
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