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Effects of TGF-β1 Ribbon Antisense on CCl(4)-induced Liver Fibrosis
Ribbon-type antisense oligonucleotide to TGF-β1 (TGF-β1 RiAS) was designed and tested to prevent or resolve the fibrotic changes induced by CCl4 injection. When Hepa1c1c7 cells were transfected with TGF-β1 RiAS, the level of TGF-β1 mRNA was effectively reduced. TGF-β1 RiAS, mismatched RiAS, and norm...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Korean Physiological Society and The Korean Society of Pharmacology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2817527/ https://ncbi.nlm.nih.gov/pubmed/20157387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2008.12.1.1 |
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