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Feasibility of long-term storage of graded information by the Ca2+/calmodulin-dependent protein kinase molecules of the postsynaptic density.

The feasibility of long-term information storage by brain type II Ca2+/calmodulin-dependent protein kinase molecules is explored. Recent evidence indicates that this protein has switch-like properties. Equations are derived showing that a single kinase holoenzyme could form a bistable switch having...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Lisman, J E, Goldring, M A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1988
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281742/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3393540/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.14.5320
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