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Therapeutic agents with dramatic antiretroviral activity and little toxicity at effective doses: aromatic polycyclic diones hypericin and pseudohypericin.

Two aromatic polycyclic diones hypericin and pseudohypericin have potent antiretroviral activity; these substances occur in plants of the Hypericum family. Both compounds are highly effective in preventing viral-induced manifestations that follow infections with a variety of retroviruses in vivo and...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Meruelo, D, Lavie, G, Lavie, D
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1988
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281723/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2839837/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.14.5230
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