Stoichiometric Quantification of Akt Phosphorylation Using LC-MS/MS

[Image: see text] The Ptdlns-3-kinase (PI3-K) signaling pathway plays a vital role in cell survival, proliferation, apoptosis and differentiation in normal cells, as well as in diseases such as cancer and diabetes. Quantification of phospho-Akt is a standard way of assessing the activity of the PI3-...

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Autori principali: Atrih, Abdelmadjid, Turnock, Dan, Sellar, Grant, Thompson, Alastair, Feuerstein, Giora, Ferguson, Michael A. J., Huang, Jeffrey T.-J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2009
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816933/
https://ncbi.nlm.nih.gov/pubmed/19902931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr900572h
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