Detection of YMDD Motif Mutants by Oligonucleotide Chips in Lamivudine-Untreated Patients with Chronic Hepatitis B Virus Infection

Lamivudine, a nucleoside analogue, has been used widely as an effective antiviral agent for the treatment of patients with chronic hepatitis B virus (HBV) infection. However, the YMDD motif mutation of HBV polymerase resistant to lamivudine occurs very frequently after long term therapy. We develope...

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Autors principals: Heo, Jeong, Cho, Mong, Kim, Hyung Hoi, Shin, Young Min, Jang, Hyun Jung, Park, Hee Kyung, Kim, Cheol Min, Kim, Gwang Ha, Kang, Dae Hwan, Song, Geun Am, Yang, Ung Suk
Format: Artigo
Idioma:Inglês
Publicat: The Korean Academy of Medical Sciences 2004
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816888/
https://ncbi.nlm.nih.gov/pubmed/15308845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2004.19.4.541
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