GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRβ in the hepatic acute phase response

The orphan receptor LRH-1 and the oxysterol receptors LXRα and LXRβ are established transcriptional regulators of lipid metabolism that appear to control inflammatory processes. Here, we investigate the anti-inflammatory actions of these nuclear receptors in the hepatic acute phase response (APR). W...

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Detalhes bibliográficos
Main Authors: Venteclef, Nicolas, Jakobsson, Tomas, Ehrlund, Anna, Damdimopoulos, Anastasios, Mikkonen, Laura, Ellis, Ewa, Nilsson, Lisa-Mari, Parini, Paolo, Jänne, Olli A., Gustafsson, Jan-Åke, Steffensen, Knut R., Treuter, Eckardt
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816737/
https://ncbi.nlm.nih.gov/pubmed/20159957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.545110
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