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Dynamic PER repression mechanisms in the Drosophila circadian clock: from on-DNA to off-DNA

Transcriptional feedback loops are central to the generation and maintenance of circadian rhythms. In animal systems as well as Neurospora, transcriptional repression is believed to occur by catalytic post-translational events. We report here in the Drosophila model two different mechanisms by which...

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Detalhes bibliográficos
Main Authors: Menet, Jerome S., Abruzzi, Katharine C., Desrochers, Jennifer, Rodriguez, Joseph, Rosbash, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816735/
https://ncbi.nlm.nih.gov/pubmed/20159956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1883910
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