Structural and Biochemical Characterization of SrcA, a Multi-Cargo Type III Secretion Chaperone in Salmonella Required for Pathogenic Association with a Host

Many Gram-negative bacteria colonize and exploit host niches using a protein apparatus called a type III secretion system (T3SS) that translocates bacterial effector proteins into host cells where their functions are essential for pathogenesis. A suite of T3SS-associated chaperone proteins bind carg...

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Main Authors: Cooper, Colin A., Zhang, Kun, Andres, Sara N., Fang, Yuan, Kaniuk, Natalia A., Hannemann, Mandy, Brumell, John H., Foster, Leonard J., Junop, Murray S., Coombes, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816692/
https://ncbi.nlm.nih.gov/pubmed/20140193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000751
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