Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency

Biogenesis of lysosome-related organelles complex 1 (BLOC-1) is a protein complex formed by the products of eight distinct genes. Loss-of-function mutations in two of these genes, DTNBP1 and BLOC1S3, cause Hermansky–Pudlak syndrome, a human disorder characterized by defective biogenesis of lysosome-...

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Bibliografiska uppgifter
Huvudupphovsmän: Cheli, Verónica T., Daniels, Richard W., Godoy, Ruth, Hoyle, Diego J., Kandachar, Vasundhara, Starcevic, Marta, Martinez-Agosto, Julian A., Poole, Stephen, DiAntonio, Aaron, Lloyd, Vett K., Chang, Henry C., Krantz, David E., Dell'Angelica, Esteban C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2010
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816613/
https://ncbi.nlm.nih.gov/pubmed/20015953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp555
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