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Genes required for B cell development
Mutations in a variety of genes can cause congenital agammaglobulinemia and a failure of B cell development. The currently known genes encode components of the pre–B cell receptor or proteins that are activated by cross-linking of the pre–B cell receptor. Defects in these genes result in a block in...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC281652/ https://ncbi.nlm.nih.gov/pubmed/14660738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200320408 |
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