Generation of Dopamine Neurons with Improved Cell Survival and Phenotype Maintenance Using a Degradation-Resistant Nurr1 Mutant

Nurr1 is a transcription factor specific for the development and maintenance of the midbrain dopamine (DA) neurons. Exogenous Nurr1 in neural precursor (NP) cells induces the differentiation of DA neurons in vitro that are capable of reversing motor dysfunctions in a rodent model for Parkinson disea...

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Bibliografske podrobnosti
Main Authors: Jo, A-Young, Kim, Mi-Young, Lee, Hyun-Seob, Rhee, Yong-Hee, Lee, Jeong-Eun, Baek, Kwang-Hyun, Park, Chang-Hwan, Koh, Hyun-Chul, Shin, Incheol, Lee, Yong-Sung, Lee, Sang-Hun
Format: Artigo
Jezik:Inglês
Izdano: Wiley Subscription Services, Inc., A Wiley Company 2009
Teme:
Tissue-Specific Stem Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816355/
https://ncbi.nlm.nih.gov/pubmed/19522012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.146
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