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Engineering of a Water-Soluble Plant Cytochrome P450, CYP73A1, and NMR-Based Orientation of Natural and Alternate Substrates in the Active Site

CYP73A1 catalyzes cinnamic acid hydroxylation, a reaction essential for the synthesis of lignin monomers and most phenolic compounds in higher plants. The native CYP73A1, initially isolated from Jerusalem artichoke (Helianthus tuberosus), was engineered to simplify purification from recombinant yeas...

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Podrobná bibliografie
Hlavní autoři: Schoch, Guillaume A., Attias, Roger, Belghazi, Maya, Dansette, Patrick M., Werck-Reichhart, Danièle
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Plant Biologists 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC281615/
https://ncbi.nlm.nih.gov/pubmed/14576280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.103.020305
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