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Crystallization and preliminary X-ray crystallographic analysis of a highly specific serpin from the beetle Tenebrio molitor

The Toll signalling pathway, which is crucial for innate immunity, is transduced in insect haemolymph via a proteolytic cascade consisting of three serine proteases. The proteolytic cascade is downregulated by a specific serine protease inhibitor (serpin). Recently, the serpin SPN48 was found to sho...

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Bibliographische Detailangaben
Hauptverfasser: Park, Sun Hee, Piao, Shunfu, Kwon, Hyun-Mi, Kim, Eun-Hye, Lee, Bok Luel, Ha, Nam-Chul
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815692/
https://ncbi.nlm.nih.gov/pubmed/20124722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109053147
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