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Crystallization and preliminary X-ray diffraction analysis of salutaridine reductase from the opium poppy Papaver somniferum

The opium poppy Papaver somniferum is the source of the narcotic analgesics morphine and codeine. Salutaridine reductase (SalR; EC 1.1.1.248) reduces the C-7 keto group of salutaridine to the C-7 (S)-hydroxyl group of salutaridinol in the biosynthetic pathway that leads to morphine in the opium popp...

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Detalhes bibliográficos
Main Authors: Higashi, Yasuhiro, Smith, Thomas J., Jez, Joseph M., Kutchan, Toni M.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815683/
https://ncbi.nlm.nih.gov/pubmed/20124713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910904932X
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