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Integrated Detection of Extended-Spectrum-Beta-Lactam Resistance by DNA Microarray-Based Genotyping of TEM, SHV, and CTX-M Genes

Extended-spectrum beta-lactamases (ESBL) of the TEM, SHV, or CTX-M type confer resistance to beta-lactam antibiotics in Gram-negative bacteria. The activity of these enzymes against beta-lactam antibiotics and their resistance against inhibitors can be influenced by genetic variation at the single-n...

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Main Authors: Leinberger, Dirk M., Grimm, Verena, Rubtsova, Maya, Weile, Jan, Schröppel, Klaus, Wichelhaus, Thomas A., Knabbe, Cornelius, Schmid, Rolf D., Bachmann, Till T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815585/
https://ncbi.nlm.nih.gov/pubmed/20007393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00765-09
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