Serotyping Pneumococcal Meningitis Cases in the African Meningitis Belt by Use of Multiplex PCR with Cerebrospinal Fluid

We reformulated a multiplex PCR algorithm for serotyping of pneumococcal meningitis directly on cerebrospinal fluid (CSF). Compared to established methods on isolates, CSF-based PCR had at least 80% sensitivity and 100% specificity. In regional meningitis surveillance, CSF-based PCR increased the se...

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Bibliographische Detailangaben
Hauptverfasser: Njanpop Lafourcade, Berthe-Marie, Sanou, Oumarou, van der Linden, Mark, Levina, Natalia, Karanfil, Meryem, Yaro, Seydou, Tamekloe, Tsidi A., Mueller, Judith E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Bacteriology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815583/
https://ncbi.nlm.nih.gov/pubmed/20007384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01402-09
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