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Mutations of tropomyosin 3 (TPM3) are common and associated with type 1 myofiber hypotrophy in congenital fiber type disproportion

Congenital fiber type disproportion (CFTD) is a rare congenital myopathy characterized by hypotonia and generalized muscle weakness. Pathologic diagnosis of CFTD is based on the presence of type 1 fiber hypotrophy of at least 12% in the absence of other notable pathological findings. Mutations of th...

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Detalhes bibliográficos
Main Authors: Lawlor, Michael W., DeChene, Elizabeth T., Roumm, Emily, Geggel, Amelia S., Moghadaszadeh, Behzad, Beggs, Alan H
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815199/
https://ncbi.nlm.nih.gov/pubmed/19953533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.21157
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