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The effect of HLA homozygosity on rubella vaccine-induced humoral and cell-mediated immune responses

Human Leukocyte Antigen (HLA) genes play a critical role in host immunity including vaccine responses. HLA molecules present antigenic peptides to T cells and provide inhibitory signals to NK cells, and polymorphisms within HLA genes allows for binding and presentation of a diverse array of self and...

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Hlavní autoři: Kennedy, Richard B., Ovsyannikova, Inna G., Vierkant, Robert A., Jacobson, Robert M., Poland, Gregory A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815167/
https://ncbi.nlm.nih.gov/pubmed/19896518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2009.11.002
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