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Shiga Toxin 1 Interaction with Enterocytes Causes Apical Protein Mistargeting through the Depletion of Intracellular Galectin-3

Shiga toxins (Stx) 1 and 2 are responsible for intestinal and systemic sequelae of infection by enterohemorrhagic Escherichia coli (EHEC). However, the mechanisms through which enterocytes are damaged remain unclear. While secondary damage from ischemia and inflammation are postulated mechanisms for...

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Detalhes bibliográficos
Main Authors: Laiko, Marina, Murtazina, Rakhilya, Malyukova, Irina, Zhu, Chengru, Boedeker, Edgar C., Gutsal, Oksana, O’Malley, Robert, Cole, Robert N., Tarr, Phillip I., Murray, Karen F., Kane, Anne, Donowitz, Mark, Kovbasnjuk, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815162/
https://ncbi.nlm.nih.gov/pubmed/19744479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.09.002
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