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Biodistribution of HuCC49ΔCH2-β-galactosidase in colorectal cancer xenograft model
Antibody-enzyme conjugate (AbE) has been widely studied for site-specific prodrug activation in tumors. The purpose of this study is to characterize the pharmacokinetics and tissue distribution of HuCC49ΔCH2-β-galactosidase conjugate. HuCC49ΔCH2 and β-galactosidase were chemically conjugated and inj...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2815147/ https://ncbi.nlm.nih.gov/pubmed/19944136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2009.11.020 |
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