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Gemfibrozil Concentrations are Significantly Decreased in the Presence of Lopinavir/ritonavir

OBJECTIVE: To determine the influence of a two-week course of lopinavir-ritonavir on the pharmacokinetics of the triglyceride-lowering agent, gemfibrozil. METHODS: The study was conducted as an open label, single-sequence pharmacokinetic study in healthy human volunteers. Gemfibrozil pharmacokinetic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Busse, Kristin H., Hadigan, Colleen, Chairez, Cheryl, Alfaro, Raul M., Formentini, Elizabeth, Kovacs, Joseph A., Penzak, Scott R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815103/
https://ncbi.nlm.nih.gov/pubmed/19648824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3181b0610e
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