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Mechanisms of Rapid Sensory Hair-Cell Death Following Co-administration of Gentamicin and Ethacrynic Acid
Concurrent administration of a high dose of gentamicin (GM; 125 mg/kg IM) and ethacrynic acid (EA; 40 mg/kg IV) results in rapid destruction of virtually all cochlear hair cells; however, the cell death signaling pathways underlying this rapid form of hair-cell degeneration are unclear. To elucidate...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814920/ https://ncbi.nlm.nih.gov/pubmed/19715747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2009.08.008 |
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