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The Protective Role of Pregnane X Receptor in Lipopolysaccharide/D-galactosamine-induced Acute Liver Injury
The pregnane x receptor (PXR) is a nuclear receptor transcription factor regulating drug-metabolizing enzymes and transporters that facilitate xenobiotic and endobiotic detoxification. Recent studies demonstrate that PXR is important in abrogating intestinal tissue damage. This study examines the ro...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814901/ https://ncbi.nlm.nih.gov/pubmed/19997066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2009.129 |
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