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Overexpression of Thioredoxins 1 and 2 Increases Retinal Ganglion Cell Survival after Pharmacologically Induced Oxidative Stress, Optic Nerve Transection, and in Experimental Glaucoma

PURPOSE: Oxidative damage is implicated in retinal ganglion cell (RGC) death after optic nerve transection (ONT) and in glaucoma. We analyzed the expression and protective effects of thioredoxins (TRXs), regulators of the cellular reduction-oxidative (redox) state, in RGCs damaged by pharmacological...

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Detalhes bibliográficos
Main Authors: Caprioli, Joseph, Munemasa, Yasunari, Kwong, Jacky M. K., Piri, Natik
Formato: Artigo
Idioma:Inglês
Publicado em: The American Ophthalmological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814564/
https://ncbi.nlm.nih.gov/pubmed/20126492
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