Targeting Allergen to FcγRI Reveals a Novel Th2 Regulatory Pathway Linked to TSLP Receptor

BACKGROUND: The molecule H22-Fel d 1, which targets cat allergen to FcγRI on dendritic cells, has the potential to treat cat allergy owing to its T-cell modulatory properties. OBJECTIVE: To investigate whether the T-cell response induced by H22-Fel d 1 is altered in the presence of the Th2-promoting...

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Hauptverfasser: Hulse, Kathryn E., Reefer, Amanda J., Engelhard, Victor H., Patrie, James T., Ziegler, Steven F., Chapman, Martin D., Woodfolk, Judith A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814452/
https://ncbi.nlm.nih.gov/pubmed/20109752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.10.027
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