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DIFFERENTIAL REGULATED INTERACTIONS OF CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II WITH ISOFORMS OF VOLTAGE GATED CALCIUM CHANNEL BETA SUBUNITS
Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) phosphorylates the β(2a) subunit of voltage-gated Ca(2+) channels at Thr498 to facilitate cardiac L-type Ca(2+) channels. CaMKII colocalizes with β(2a) in cardiomyocytes and also binds to a domain in β(2a) that contains Thr498 and exhibits amino...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814322/ https://ncbi.nlm.nih.gov/pubmed/18205403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701755q |
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