Cholesterol as Treatment for Pneumococcal Keratitis: Cholesterol-Specific Inhibition of Pneumolysin in the Cornea

PURPOSE: The purpose of this study was to determine whether cholesterol, the host cell receptor for pneumolysin of Streptococcus pneumoniae, could effectively treat pneumococcal keratitis. METHODS: New Zealand White rabbits were intrastromally injected with 10(5) colony-forming units (CFUs) of S. pn...

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Bibliographic Details
Main Authors: Marquart, Mary E., Monds, Kathryn S., McCormick, Clare C., Dixon, Sherrina N., Sanders, Melissa E., Reed, Julian M., McDaniel, Larry S., Caballero, Armando R., O'Callaghan, Richard J.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814300/
https://ncbi.nlm.nih.gov/pubmed/17525197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-0017
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