Susceptibility to Crohn’s Disease is Mediated by KIR2DL2/KIR2DL3 Heterozygosity and the HLA-C Ligand

In the present study, we investigated the relationship between the KIR loci and the genes encoding their HLA ligands and genetic susceptibility to Crohn’s disease (CD). Analyses of the interactions between KIR3DL1, KIR2DL1, KIR2DL2 and KIR2DL3 with their respective HLA ligands indicate that there is...

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Hauptverfasser: Hollenbach, Jill A., Ladner, Martha B., Saeteurn, Koy, Taylor, Kent D., Mei, Ling, Haritunians, Talin, McGovern, Dermot PB, Erlich, Henry A., Rotter, Jerome I., Trachtenberg, Elizabeth A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813946/
https://ncbi.nlm.nih.gov/pubmed/19789864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-009-0396-5
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