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INDUCTION OF HYPERTENSION AND PERIPHERAL INFLAMMATION BY REDUCTION OF EXTRACELLULAR SUPEROXIDE DISMUTASE IN THE CENTRAL NERVOUS SYSTEM

The circumventricular organs (CVO) lack a well-formed blood-brain barrier and produce superoxide (O(2)(•−)) in response to angiotensin II and other hypertensive stimuli. This increase in central O(2)(•−) has been implicated in regulation of blood pressure. The extracellular superoxide dismutase (SOD...

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Bibliografische gegevens
Hoofdauteurs: Lob, Heinrich E., Marvar, Paul J., Guzik, Tomasz J., Sharma, Shraya, McCann, Louise A., Weyand, Cornelia, Gordon, Frank J., Harrison, David G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813894/
https://ncbi.nlm.nih.gov/pubmed/20008675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.142646
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