Chronic inflammation and estradiol interact through MAPK activation to affect TMJ nociceptive processing by trigeminal caudalis neurons

The mitogen-activated protein kinase/extracellular regulated kinase (MAPK/ERK) pathway plays a key role in mediating estrogen actions in the brain and neuronal sensitization during inflammation. Estrogen status is a risk factor in chronic temporomandibular muscle/joint disorders (TMJD); however, the...

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Bibliographic Details
Main Authors: Tashiro, A., Okamoto, K., Bereiter, D.A.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813765/
https://ncbi.nlm.nih.gov/pubmed/19786077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.09.058
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