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PTEN status in advanced colorectal cancer treated with cetuximab
BACKGROUND: Loss of phosphatase and tensin homologue deleted in chromosome 10 (PTEN) function in advanced colorectal cancer (CRC) may represent one of the resistance mechanisms to cetuximab by interfering with the epidermal growth factor receptor signal transduction pathway. METHODS: PTEN expression...
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Principais autores: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2813733/ https://ncbi.nlm.nih.gov/pubmed/19953097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605471 |
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