Schistosoma japonicum-infected mice show reduced hepatic fibrosis and eosinophilia and selective inhibition of interleukin-5 secretion by CD4+ cells after treatment with anti-interleukin-2 antibodies.

Schistosoma japonicum-infected mice were injected with antibodies to interleukin-2 (IL-2) and/or IL-2 receptor to clarify the role of IL-2 on the granulomatous reaction around schistosome eggs in the liver. Granulomas were of normal or slightly increased size in animals subjected to IL-2 blockade, b...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Cheever, A W, Xu, Y, Sher, A, Finkelman, F D, Cox, T M, Macedonia, J G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281360/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8095922/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.4.1288-1292.1993
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