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Arginine Grafting to Endow Cell-Permeability

We report on a means to endow proteins with the ability to permeate mammalian cells without appending an exogenous domain. Our approach is to install a cationic patch on the surface of a target protein by the grafting of arginine residues. Doing so with green fluorescent protein (GFP) did not compro...

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Bibliografiska uppgifter
Huvudupphovsmän: Fuchs, Stephen M., Raines, Ronald T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813566/
https://ncbi.nlm.nih.gov/pubmed/17319644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb600429k
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