Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

Monozygotic (MZ) twins are partially concordant for most complex diseases, including autoimmune disorders. Whereas phenotypic concordance can be used to study heritability, discordance suggests the role of non-genetic factors. In autoimmune diseases, environmentally driven epigenetic changes are tho...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Javierre, Biola M., Fernandez, Agustin F., Richter, Julia, Al-Shahrour, Fatima, Martin-Subero, J. Ignacio, Rodriguez-Ubreva, Javier, Berdasco, Maria, Fraga, Mario F., O'Hanlon, Terrance P., Rider, Lisa G., Jacinto, Filipe V., Lopez-Longo, F. Javier, Dopazo, Joaquin, Forn, Marta, Peinado, Miguel A., Carreño, Luis, Sawalha, Amr H., Harley, John B., Siebert, Reiner, Esteller, Manel, Miller, Frederick W., Ballestar, Esteban
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2010
Gaiak:
Letter
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813473/
https://ncbi.nlm.nih.gov/pubmed/20028698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.100289.109
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