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Superoxide Production by Mitochondria of Insulin Sensitive Tissues: Mechanistic Differences and Effect of Early Diabetes
Obesity and mild hyperglycemia are characteristic of early or “prediabetes”. The associated increase in fatty acid flux is posited to enhance substrate delivery to mitochondria leading to enhanced superoxide production resulting in mitochondrial dysfunction and progressive worsening of the hyperglyc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2813404/ https://ncbi.nlm.nih.gov/pubmed/19765776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2009.07.021 |
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