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Glutamate permeability at the blood-brain barrier in insulinopenic and insulin-resistant rats

The influence of diabetes on brain glutamate (GLU) uptake was studied in insulinopenic (streptozotocin (STZ)) and insulin-resistant (diet-induced obesity (DIO)) rat models of diabetes. In the STZ study, adult male Sprague-Dawley rats were treated with STZ (65 mg/kg iv) or vehicle and studied 3 weeks...

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Detalhes bibliográficos
Main Authors: Hawkins, Richard A., Mokashi, Ashwini, DeJoseph, Mary R., Viña, Juan R., Fernstrom, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813370/
https://ncbi.nlm.nih.gov/pubmed/19793593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2009.07.022
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