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Young age and low temperature, but not female gender delay ATP loss and glutamate release, and protect Purkinje cells during simulated ischemia in cerebellar slices

Excessive activation of glutamate receptors contributes to Purkinje cell (PC) damage during brain ischemia, but the mechanisms of glutamate release are contentious. Age, gender and temperature all strongly influence ischemic brain damage, but the mechanisms underlying their influence are not fully u...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mohr, Claudia, Brady, James D., Rossi, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813327/
https://ncbi.nlm.nih.gov/pubmed/19825379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.09.013
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