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Attenuation of morphine antinociceptive tolerance by a CB(1) receptor agonist and an NMDA receptor antagonist: interactive effects

CB(1) cannabinoid (CB(1)) receptor agonists and N-Methyl-d-Aspartate (NMDA) receptor antagonists attenuate the development of morphine antinociceptive tolerance. The present study used dose-addition analysis to evaluate CB(1)/NMDA receptor interactions on this endpoint. Chronic morphine administrati...

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Autors principals: Fischer, Bradford D., Ward, Sara J., Henry, Fredrick E., Dykstra, Linda A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813317/
https://ncbi.nlm.nih.gov/pubmed/19699755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.08.005
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