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Use of rpsL as a Counterselectable Marker in Borrelia burgdorferi

We have demonstrated that rpsL, encoding the S12 protein of the small ribosomal subunit, can be used as a counterselectable marker in Borrelia burgdorferi, the causative agent of Lyme disease. Mutations in rpsL confer streptomycin resistance. Streptomycin susceptibility is dominant in an rpsL merodi...

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Detalhes bibliográficos
Main Authors: Drecktrah, Dan, Douglas, J. Miles, Samuels, D. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813015/
https://ncbi.nlm.nih.gov/pubmed/19966024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02172-09
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