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Key Process Conditions for Production of C(4) Dicarboxylic Acids in Bioreactor Batch Cultures of an Engineered Saccharomyces cerevisiae Strain

A recent effort to improve malic acid production by Saccharomyces cerevisiae by means of metabolic engineering resulted in a strain that produced up to 59 g liter(−1) of malate at a yield of 0.42 mol (mol glucose)(−1) in calcium carbonate-buffered shake flask cultures. With shake flasks, process par...

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Detalhes bibliográficos
Main Authors: Zelle, Rintze M., de Hulster, Erik, Kloezen, Wendy, Pronk, Jack T., van Maris, Antonius J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812985/
https://ncbi.nlm.nih.gov/pubmed/20008165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02396-09
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