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Prometaphase spindle maintenance by an antagonistic motor-dependent force balance made robust by a disassembling lamin-B envelope

We tested the classical hypothesis that astral, prometaphase bipolar mitotic spindles are maintained by balanced outward and inward forces exerted on spindle poles by kinesin-5 and -14 using modeling of in vitro and in vivo data from Drosophila melanogaster embryos. Throughout prometaphase, puncta o...

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Détails bibliographiques
Auteurs principaux: Civelekoglu-Scholey, Gul, Tao, Li, Brust-Mascher, Ingrid, Wollman, Roy, Scholey, Jonathan M.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812851/
https://ncbi.nlm.nih.gov/pubmed/20065089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200908150
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