Transferrin and lactoferrin undergo proteolytic cleavage in the Pseudomonas aeruginosa-infected lungs of patients with cystic fibrosis.

Bacterium- and neutrophil-derived proteases have been suggested to contribute to tissue injury at sites of Pseudomonas aeruginosa infection. Pseudomonas elastase cleavage of transferrin enhances in vitro iron removal from this protein by the P. aeruginosa siderophore pyoverdin. This cleavage also ge...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Principais autores:	Britigan, B E, Hayek, M B, Doebbeling, B N, Fick, R B
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281282/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8225581/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.12.5049-5055.1993
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