D-Cycloserine Improves Functional Outcome after Traumatic Brain Injury with Wide Therapeutic Window

It has been long thought that hyper-activation of N-methyl-D-aspartate (NMDA) receptors underlies neurological decline after traumatic brain injury. However, all clinical trials with NMDA receptor antagonists failed. Since NMDA receptors are down-regulated from 4h to 2 weeks after brain injury, acti...

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Hlavní autoři: Adeleye, Amos, Shohami, Esther, Nachman, Dean, Alexandrovich, Alexander, Trembovler, Victoria, Yaka, Rami, Shoshan, Yigal, Dhawan, Jasbeer, Biegon, Anat
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812686/
https://ncbi.nlm.nih.gov/pubmed/19958766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2009.11.066
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