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A Method for Solution NMR Structural Studies of Large Integral Membrane Proteins: Reverse Micelle Encapsulation

The structural study of membrane proteins perhaps represents one of the greatest challenges of the post-genomic era. While membrane proteins comprise over 50% of current and potential drug targets, their structural characterization lags far behind that of soluble proteins. Nuclear magnetic resonance...

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Autori principali: Kielec, Joseph M., Valentine, Kathleen G., Wand, A. Joshua
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812662/
https://ncbi.nlm.nih.gov/pubmed/19665988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.07.027
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