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Solid-state (2)H and (15)N NMR studies of side chain and backbone dynamics of phospholamban in lipid bilayers: investigation of the N27A mutation
Phospholamban (PLB) is an integral membrane protein regulating Ca(2+) transport through inhibitory interaction with sarco(endo)plasmic reticulum calcium ATPase (SERCA). The Asn27 to Ala (N27A) mutation of PLB has been shown to function as a superinhibitor of the affinity of SERCA for Ca(2+) and of c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812648/ https://ncbi.nlm.nih.gov/pubmed/19840770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.09.025 |
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