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Glucose activates prenyltransferases in pancreatic islet β-cells

A growing body of evidence implicates small G-proteins [e.g., Cdc42 and Rac1] in glucose-stimulated insulin secretion [GSIS] in the islet β-cell. These signaling proteins undergo post-translational modifications [e.g., prenylation] at their C-terminal cysteine residue and appear to be essential for...

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Bibliografiska uppgifter
Huvudupphovsmän: Goalstone, Marc, Kamath, Vasudeva, Kowluru, Anjaneyulu
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812622/
https://ncbi.nlm.nih.gov/pubmed/19951701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.11.159
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