Defective Secretion of Islet Hormones in Chromogranin-B Deficient Mice

Granins are major constituents of dense-core secretory granules in neuroendocrine cells, but their function is still a matter of debate. Work in cell lines has suggested that the most abundant and ubiquitously expressed granins, chromogranin A and B (CgA and CgB), are involved in granulogenesis and...

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Détails bibliographiques
Auteurs principaux: Obermüller, Stefanie, Calegari, Federico, King, Angus, Lindqvist, Anders, Lundquist, Ingmar, Salehi, Albert, Francolini, Maura, Rosa, Patrizia, Rorsman, Patrik, Huttner, Wieland B., Barg, Sebastian
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812483/
https://ncbi.nlm.nih.gov/pubmed/20126668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008936
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