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The N-Terminal Transmembrane Domain of λ S Is Required for Holin but Not Antiholin Function
The λ S gene encodes a holin, S105, and an antiholin, S107, which differs by its Met-Lys N-terminal extension. The model for the lysis-defective character of S107 stipulates that the additional N-terminal basic residue keeps S107 from assuming the topology of S105, which is N-out, C-in, with three t...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812449/ https://ncbi.nlm.nih.gov/pubmed/19897658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01263-09 |
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