Nonpathogenesis of Simian Immunodeficiency Virus Infection Is Associated with Reduced Inflammation and Recruitment of Plasmacytoid Dendritic Cells to Lymph Nodes, Not to Lack of an Interferon Type I Response, during the Acute Phase

Divergent Toll-like receptor 7 (TLR7) and TLR9 signaling has been proposed to distinguish pathogenic from nonpathogenic simian immunodeficiency virus infection in primate models. We demonstrate here that increased expression of type I interferon in pathogenic rhesus macaques compared to nonpathogeni...

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Hlavní autoři: Campillo-Gimenez, Laure, Laforge, Mireille, Fay, Michèle, Brussel, Audrey, Cumont, Marie-Christine, Monceaux, Valérie, Diop, Ousmane, Lévy, Yves, Hurtrel, Bruno, Zaunders, John, Corbeil, Jacques, Elbim, Carole, Estaquier, Jérôme
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812402/
https://ncbi.nlm.nih.gov/pubmed/19939930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01496-09
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